Search on: DNA GLYCOSYLASES 
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Descriptor English:   DNA Glycosylases 
Descriptor Spanish:   ADN Glicosilasas 
Descriptor Portuguese:   DNA Glicosilases 
Synonyms English:   DNA N-glycosidase  
Tree Number:   D08.811.074.249
D08.811.277.450.430.099
Definition English:   A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA. 
History Note English:   2004; use DNA GLYCOSIDASES (NM) 1980-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38126 
Unique Identifier:   D045647 

Occurrence in VHL: 		 

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